Article
Forceps minor region signal abnormality "ears of the lynx": an early MRI finding in spastic paraparesis with thin corpus callosum and mutations in the spatacsin gene (SPG11) on chromosome 15.
Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Jan 2009
Riverol M, Samaranch L, Pascual B, Pastor P, Irigoyen J, Pastor M A, de Castro P, Masdeu J C
Abstract excerpt
BACKGROUND AND PURPOSE: A thin corpus callosum on magnetic resonance imaging (MRI) characterizes a type of autosomal recessive disorder with progressive spastic paraparesis and cognitive impairment. Known as Hereditary Spastic Paraparesis with Thin Corpus Callosum (HSP-TCC), it has been associated with mutations of the SPG11 gene. No other specific MRI findings have been reported. METHODS: We studied with MRI...
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