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Article

Carboplatin-induced gene expression changes in vitroare prognostic of survival in epithelial ovarian cancer

28 Nov 2008

Abstract excerpt

BACKGROUND: We performed a time-course microarray experiment to define the transcriptional response to carboplatin in vitro, and to correlate this with clinical outcome in epithelial ovarian cancer (EOC). RNA was isolated from carboplatin and control-treated 36M2 ovarian cancer cells at several time points, followed by oligonucleotide microarray hybridization. Carboplatin induced changes in gene expression were...

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PMID: 19038057
DOI: 10.1186/1755-8794-1-59

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