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Article

Brain-derived neurotrophic factor: the neurotrophin hypothesis of psychopathology.

CNS spectrums - 1 Nov 2008

Stein Dan J, Daniels Willie M U, Savitz Jonathan, Harvey Brian H

Abstract excerpt

While monoaminergic hypotheses of psychopathology remain popular, there has been growing interest in the role of neurotrophins in neuropsychiatric disorders. Basic laboratory work has documented the importance of neurotrophins in neuronal survival and synaptic plasticity, and a range of clinical studies has provided analogous evidence of their role in neuropathology. Work on gene variants in brain-derived...

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PMID: 19037180
DOI: 10.1017/s1092852900013997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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