Article
Emerging Roles of Nodal and Cripto-1: From Embryogenesis to Breast Cancer Progression
31 Oct 2008
Abstract excerpt
Breast carcinoma cells and embryonic progenitors similarly implement stem cell-associated signaling pathways to sustain continued growth and plasticity. Indeed, recent studies have implicated signaling pathways, including those associated with the Notch, and Transforming Growth Factor-Beta (TGF-beta) superfamilies, as instrumental to both embryological development and breast cancer progression. In particular,...
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