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Article

Doppel gene polymorphisms in Portuguese sheep breeds: insights on ram fertility.

Animal reproduction science - 1 Aug 2009

Pereira R M, Mesquita P, Batista M, Baptista M C, Barbas J P, Pimenta J, Santos I C, Marques M R, Vasques M I, Silva Pereira M, Santos Silva F, Oliveira Sousa M C, Fontes C M G, Horta A E M, Prates J A M, Marques C C

Abstract excerpt

Transgenic knockout of the gene encoding the prion-like protein Doppel leads to male infertility in mice. The precise role of Doppel in male fertility is still unclear, but sperm from Doppel-deficient mice appear to be unable to undergo the normal acrosome reaction necessary to penetrate the zona...

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PMID: 19028030
DOI: 10.1016/j.anireprosci.2008.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19028030-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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