Article
Myotoxicity of lipid-lowering agents in a teenager with MELAS mutation.
Pediatric neurology - 1 Dec 2008
Tay Stacey K H, Dimauro Salvatore, Pang Aileen Y W, Lai Poh-San, Yap Hui-Kim
Abstract excerpt
The use of lipid-lowering statins has been associated with raised serum muscle enzymes and, occasionally, with rhabdomyolysis, especially in patients with pre-existing metabolic myopathies. The A3243G mutation is one of the most common mutations associated with mitochondrial disorders. A teenager harboring the A3243G mutation had the unusual association of hereditary glomerulopathy and recurrent episodes of...
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