Article
Association between the AGTR1 polymorphism +1166A>C and serum levels of high-sensitivity C-reactive protein.
Regulatory peptides - 8 Jan 2009
Suchankova Petra, Henningsson Susanne, Olsson Marie, Baghaei Fariba, Rosmond Roland, Holm Göran, Eriksson Elias, Ekman Agneta
Abstract excerpt
Genetic factors have been shown to influence high-sensitivity C-reactive protein (hsCRP) levels, however, which genes that are involved in this process remains to be clarified. The renin-angiotensin system (RAS) is of importance for the regulation of inflammation, and blockade of angiotensin II type 1 receptors (AGTR1) influences hsCRP levels. These findings prompted us to investigate whether a polymorphism in...
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