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Article

The isolation and partial characterization of a rat incisor dentin matrix polypeptide with in vitro chondrogenic activity.

The Journal of biological chemistry - 5 May 1991

Amar S, Sires B, Sabsay B, Clohisy J, Veis A

Abstract excerpt

In vivo implants of demineralized dentin matrix into muscle induce the formation of bone within the muscle. As with bone matrix implants, the bone induction appears to follow a chondrogenic pathway. Outgrowth cells from explants of neonatal rat muscle respond to bone matrix, in vitro, by expressing a heightened synthesis of sulfated proteoglycans and type II collagen, phenotypic of cartilage. The in vitro cell...

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PMID: 1902476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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