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Article

Genetic polymorphisms of MC2R gene associated with responsiveness to adrenocorticotropic hormone therapy in infantile spasms.

Chinese medical journal - 5 Sept 2008

Liu Zhan-Li, He Bing, Fang Fang, Tang Cai-Yun, Zou Li-Ping

Abstract excerpt

BACKGROUND: Infantile spasms is a severe epileptic encephalopathy, which is refractory to conventional antiepileptic drugs. Adrenocorticotropic hormone (ACTH) has been the major therapy for infantile spasms; however, ACTH therapy is ineffective for some patients. The variations in the receptor genes can contribute to antiepileptic drug resistance. This study was to elucidate the possible associations between the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19024088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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