Article
The joint association between F5 gene polymorphisms and maternal smoking during pregnancy on preterm delivery.
Human genetics - 1 Jan 2009
Yu Yunxian, Tsai Hui-Ju, Liu Xin, Mestan Karen, Zhang Shanchun, Pearson Colleen, Ortiz Katherin, Xu Xiping, Zuckerman Barry, Wang Xiaobin
Abstract excerpt
Factor V (F5) genetic variants and maternal smoking during pregnancy individually has been associated with increased risk of preterm delivery (PTD). We hypothesize that F5 gene and maternal smoking may synergistically increase the risk of PTD. Three single nucleotide polymorphisms (SNPs) in F5 gene (rs6019, rs2213869 and rs6022) were genotyped in 542 mothers with PTD and 1,141 mothers with term deliveries at the...
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