Article
Natural selection governs local, but not global, evolutionary gene coexpression networks in Caenorhabditis elegans.
BMC systems biology - 13 Nov 2008
Jordan I King, Katz Lee S, Denver Dee R, Streelman J Todd
Abstract excerpt
BACKGROUND: Large-scale evaluation of gene expression variation among Caenorhabditis elegans lines that have diverged from a common ancestor allows for the analysis of a novel class of biological networks - evolutionary gene coexpression networks. Comparative analysis of these evolutionary networks has the potential to uncover the effects of natural selection in shaping coexpression network topologies since C....
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