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Article

Widespread balancing selection and pathogen-driven selection at blood group antigen genes.

Genome research - 1 Feb 2009

Fumagalli Matteo, Cagliani Rachele, Pozzoli Uberto, Riva Stefania, Comi Giacomo P, Menozzi Giorgia, Bresolin Nereo, Sironi Manuela

Abstract excerpt

Historically, allelic variations in blood group antigen (BGA) genes have been regarded as possible susceptibility factors for infectious diseases. Since host-pathogen interactions are major determinants in evolution, BGAs can be thought of as selection targets. In order to verify this hypothesis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 18997004
DOI: 10.1101/gr.082768.108
PMCID: PMC2652214

Genes

BSG
FUT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18997004-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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