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Article

The induction of nitric oxide response of carp macrophages by transferrin is influenced by the allelic diversity of the molecule.

Fish & shellfish immunology - 1 Apr 2009

Jurecka Patrycja, Irnazarow Ilgiz, Stafford James L, Ruszczyk Aleksandra, Taverne Nico, Belosevic Miodrag, Savelkoul Huub F J, Wiegertjes Geert F

Abstract excerpt

The central role of transferrin (Tf) as an iron transporting protein has been extended by observations that modified versions of Tf also participate in the regulation of innate immunity. We report on the isolation of two carp Tf proteins (alleles D and G) to purity using rivanol precipitation and ion-exchange chromatography, and describe the activation of head kidney-derived carp macrophages by cleaved Tf. We...

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PMID: 18996204
DOI: 10.1016/j.fsi.2008.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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