Article
A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis.
Neurology - 6 Jan 2009
Mitchell R M, Freeman W M, Randazzo W T, Stephens H E, Beard J L, Simmons Z, Connor J R
Abstract excerpt
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with complicated pathogenesis that poses challenges with respect to diagnosis and monitoring of disease progression. OBJECTIVES: To identify a biomarker panel that elucidates ALS disease pathogenesis, distinguishes patients with ALS from neurologic disease controls, and correlates with ALS disease characteristics, and to...
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