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Article

Mood changes after delivery: role of the serotonin transporter gene

31 Oct 2008

Abstract excerpt

BACKGROUND: Polymorphic variations in the serotonin transporter gene (5-HTT) moderate the depressogenic effects of tryptophan depletion. After childbirth there is a sharp reduction in brain tryptophan availability, thus polymorphic variations in 5-HTT may play a similar role in the post-partum period. AIMS: To study the role of 5-HTT polymorphic variations in mood changes after delivery. METHOD: One thousand,...

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PMID: 18978318
DOI: 10.1192/bjp.bp.107.045427

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