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Article

Trends in prokaryotic evolution revealed by comparison of closely related bacterial and archaeal genomes.

Journal of bacteriology - 1 Jan 2009

Novichkov Pavel S, Wolf Yuri I, Dubchak Inna, Koonin Eugene V

Abstract excerpt

In order to explore microevolutionary trends in bacteria and archaea, we constructed a data set of 41 alignable tight genome clusters (ATGCs). We show that the ratio of the medians of nonsynonymous to synonymous substitution rates (dN/dS) that is used as a measure of the purifying selection pressure on protein sequences is a stable characteristic of the ATGCs. In agreement with previous findings, parasitic...

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Identifiers

PMID: 18978059
DOI: 10.1128/JB.01237-08
PMCID: PMC2612427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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