Article
SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics.
Malaria journal - 20 Oct 2020
Fola Abebe A, Kattenberg Eline, Razook Zahra, Lautu-Gumal Dulcie, Lee Stuart, Mehra Somya, Bahlo Melanie, Kazura James, Robinson Leanne J, Laman Moses, Mueller Ivo, Barry Alyssa E
Abstract excerpt
BACKGROUND: Genomic surveillance of malaria parasite populations has the potential to inform control strategies and to monitor the impact of interventions. Barcodes comprising large numbers of single nucleotide polymorphism (SNP) markers are accurate and efficient genotyping tools, however may need to be tailored to specific malaria transmission settings, since 'universal' barcodes can lack resolution at the...
Topics
- DNA Barcoding, Taxonomic
- Genetics, Population
- Humans
- Malaria, Vivax
- Microsatellite Repeats
- Plasmodium vivax
- Polymorphism, Single Nucleotide