Article
Infrequent and low expression of cancer-testis antigens located on the X chromosome in colorectal cancer: implications for immunotherapy in South African populations.
Biotechnology journal - 1 Nov 2008
Dakshinamurthy Amirtha Ganesh, Ramesar Rajkumar, Goldberg Paul, Blackburn Jonathan M
Abstract excerpt
Cancer-testis (CT) antigens are a group of tumor antigens that are expressed in the testis and aberrantly in cancerous tissue but not in somatic tissues. The testis is an immune-privileged site because of the presence of a blood-testis barrier; as a result, CT antigens are considered to be essent...
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