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Article

Absolute side-chain structure at position 13 is required for the inhibitory activity of bromein.

The Journal of biological chemistry - 26 Dec 2008

Sawano Yoriko, Hatano Ken-ichi, Miyakawa Takuya, Tanokura Masaru

Abstract excerpt

Bromelain isoinhibitor (bromein), a cysteine proteinase inhibitor from pineapple stem, has a unique double-chain structure. The bromein precursor protein includes three homologous inhibitor domains, each containing an interchain peptide between the light and heavy chains. The interchain peptide i...

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Identifiers

PMID: 18948264
DOI: 10.1074/jbc.M806748200
PMCID: PMC2662299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18948264-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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