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Article

Ancillary testing of liquid-based cytology specimens for identification of patients at high risk of cervical cancer.

Virchows Archiv : an international journal of pathology - 1 Dec 2008

Fujii Takuma, Saito Miyuki, Iwata Takashi, Hirao Nobumaru, Nishio Hiroshi, Ohno Akiko, Tsukazaki Katsumi, Mukai Makio, Kameyama Kaori, Aoki Daisuke

Abstract excerpt

Integration of human papillomavirus DNAs into the host genome is crucial to the development of cervical cancer. Overexpression of the P16 protein has been reported in cervical intraepithelial neoplasia (CIN) as well as cervical cancer. Such molecular biomarkers have been utilized for ancillary testing of liquid-based cytology specimens; however, their clinical application remains controversial. To detect CIN 2 or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18936966
DOI: 10.1007/s00428-008-0687-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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