Prospective experience with integrated prenatal screening and first trimester combined screening for trisomy 21 in a large Canadian urban center

Abstract excerpt

OBJECTIVES: To evaluate the performance of integrated prenatal screening (IPS) and first trimester combined screening (FTS) for trisomy 21 in a large Canadian urban center. METHOD: Prospective data collection on women having FTS at one center from 1 November 2003 to 31 December 2005, or IPS at another from 1 January 2003 to 31 December 2005. A positive screen was defined as adjusted risk for trisomy 21 >or= 1/200...

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