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Article

Isolation of a strain-specific Entamoeba histolytica cDNA clone

1 Apr 1991

Abstract excerpt

Entamoeba histolytica is an intestinal parasite causing significant morbidity and mortality worldwide. More tools are needed to understand the epidemiology and molecular pathogenesis of amebiasis. A cDNA library was constructed by using poly(A)+ RNA isolated from an axenic strain of E. histolytica, HM1:IMSS, which expresses a pathogenic isoenzyme pattern (zymodeme). Differential screening of the library yielded a...

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PMID: 1890170
DOI: 10.1128/jcm.29.4.696-701.1991

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