Article
Exact solution of a model DNA-inversion genetic switch with orientational control.
Physical review letters - 12 Sept 2008
Visco Paolo, Allen Rosalind J, Evans Martin R
Abstract excerpt
DNA inversion is an important mechanism by which bacteria and bacteriophage switch reversibly between phenotypic states. In such switches, the orientation of a short DNA element is flipped by a site-specific recombinase enzyme. We propose a simple model for a DNA-inversion switch in which recombinase production is dependent on the switch state (orientational control). Our model is inspired by the fim switch in E....
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