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Article

Known susceptibility SNPs for sporadic prostate cancer show a similar association with "hereditary" prostate cancer.

The Prostate - 1 Apr 2015

Cremers Ruben G, Galesloot Tessel E, Aben Katja K, van Oort Inge M, Vasen Hans F, Vermeulen Sita H, Kiemeney Lambertus A

Abstract excerpt

BACKGROUND: More than 70 single nucleotide polymorphisms (SNPs) have been reported to be associated with prostate cancer (PC) risk; these were mainly identified in the general population with predominantly sporadic PC (SPC). Previous studies have suggested similar associations between a selection of these SNPs and hereditary PC (HPC). Our aim was to evaluate the effect of all known PC risk SNPs and their...

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PMID: 25560306
DOI: 10.1002/pros.22933
PMCID: PMC6680338

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