Article
[Tumor necrosis factor gene polymorphisms in breast cancer patients].
Genetika - 1 Sept 2008
Ostashkin A S, Malivanova T F, Iurchenko V A, Mazurenko N N
Abstract excerpt
Analysis of microsatellite TNFalpha marker and (-308(G/A) polymorphisms in promoter of TNFalpha gene was conducted in 167 patients with various types of sporadic breast cancer (BC) as well as in 139 healthy Russian donors. It was shown that frequency of allele 7 in TNFalpha microsatellite marker was significantly higher in BC patients than in healthy donors (17.9% versus 10.4%; P = 0.02) mainly due to the...
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