Article
Does performance on the standard antisaccade task meet the co-familiality criterion for an endophenotype?
Brain and cognition - 1 Dec 2008
Levy Deborah L, Bowman Elizabeth A, Abel Larry, Krastoshevsky Olga, Krause Verena, Mendell Nancy R
Abstract excerpt
The "co-familiality" criterion for an endophenotype has two requirements: (1) clinically unaffected relatives as a group should show both a shift in mean performance and an increase in variance compared with controls; (2) performance scores should be heritable. Performance on the antisaccade task is one of several candidate endophenotypes for schizophrenia. In this paper we examine whether the various measures of...
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