Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IgA response by oral infection with an attenuated Yersinia enterocolitica mutant: implications for its use as oral carrier vaccine.

Vaccine - 2 Dec 2008

Blanco Helga M, Lacoste María G, Eliçabe Ricardo J, Di Genaro María S

Abstract excerpt

Yersinia enterocolitica (Ye) mutant strain (sycH-) is unable to secrete the virulence protein YopH. Mucosal vaccination is often required to induce protection, but stimulating strong IgA response is frequently difficult. Here, we addressed whether Ye sycH- might induce IgA response, and investigated its attenuation in TNFRp55-/-, IL-12p40-/- and IL-4-/- mice. We found that Ye sycH- colonizes Peyer's patches, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Bacterial
Share to Bacterial Vaccines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunity, Mucosal

Share to Immunoglobulin A

Share to Interleukin-4

Share to Peyer's Patches

Share to Yersinia enterocolitica

Share to Yersinia Infections

Source

Identifiers

PMID: 18835575
DOI: 10.1016/j.vaccine.2008.09.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IgA response by oral infection with an attenuated Yersinia enterocolitica mutant: implications for its use as oral carrier vaccine.PMID 18835575Read ↗

Attenuated Yersinia enterocolitica mutant strains exhibit differential virulence in cytokine-deficient mice: implications for the development of novel live carrier vaccines.Semantic proximity Read ↗

Yersinia enterocolitica ghost with msbB mutation provides protection and reduces proinflammatory cytokines in mice.Semantic proximity Read ↗

Rational live oral carrier vaccine design by mutating virulence-associated genes of Yersinia enterocolitica.Semantic proximity Read ↗

Oral inoculation with Type III secretion mutants of Yersinia pseudotuberculosis provides protection from oral, intraperitoneal, or intranasal challenge with virulent Yersinia.Semantic proximity Read ↗

Yersinia pestis YscG protein is a Syc-like chaperone that directly binds yscE.Semantic proximity Read ↗

Status of YopM and YopN in the Yersinia Yop virulon: YopM of Y.enterocolitica is internalized inside the cytosol of PU5-1.8 macrophages by the YopB, D, N delivery apparatus.Semantic proximity Read ↗

Novel colicin Fy of Yersinia frederiksenii inhibits pathogenic Yersinia strains via YiuR-mediated reception, TonB import, and cell membrane pore formation.Semantic proximity Read ↗

Role of Yersinia enterocolitica Yst toxin in experimental infection of young rabbits.Semantic proximity Read ↗

Yersinia enterocolitica aroA mutants as carriers of the B subunit of the Escherichia coli heat-labile enterotoxin to the murine immune system.Semantic proximity Read ↗

YopP-expressing variant of Y. pestis activates a potent innate immune response affording cross-protection against yersiniosis and tularemia [corrected].Semantic proximity Read ↗

Individual chaperones required for Yop secretion by Yersinia.Semantic proximity Read ↗

Evaluation of protective immunity induced by Yersinia enterocolitica type-III secretion system mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.