Article
Characterization of Low‐Density Lipoprotein Cholesterol‐Lowering Efficacy for Atorvastatin in a Population‐Based DNA Biorepository
16 Sept 2008
Abstract excerpt
The Marshfield Clinic Personalized Medicine Research Project (PMRP) represents a large population-based biobank located in central Wisconsin. To position the PMRP database for large-scale pharmacogenetic association studies in the context of lipid-lowering therapy, we constructed an electronic phenotyping algorithm to quantify exposure and dose-response for atorvastatin, the most commonly prescribed...
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