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The PA4204 gene encodes a periplasmic gluconolactonase (PpgL) which is important for fitness of Pseudomonas aeruginosa.

Microbiology (Reading, England) - 1 Oct 2008

Tarighi Saeed, Wei Qing, Cámara Miguel, Williams Paul, Fletcher Matthew P, Kajander Tommi, Cornelis Pierre

Abstract excerpt

In Pseudomonas aeruginosa, the PA4204 gene encodes a protein with a signal peptide and a COG2706 domain of the type present in 3-carboxy-cis,cis-muconate lactonizing enzymes. A molecular model based on the structure of the Escherichia coli YbhE phosphogluconate lactonizing enzyme shows that the enzyme has a beta-propeller ('doughnut') structure and a central active site comprising one histidine, one glutamic acid...

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PMID: 18832304
DOI: 10.1099/mic.0.2008/018465-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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