Article
Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence.
American journal of human genetics - 1 Sept 1991
Dono R, Montuori N, Rocchi M, De Ponti-Zilli L, Ciccodicola A, Persico M G
Abstract excerpt
We have previously reported on the identification of a cDNA clone encoding a novel human growth factor, named "CRIPTO," that is abundantly expressed in undifferentiated human NTERA-2 clone D1 (NT2/D1) and mouse (F9) teratocarcinoma cells. We now report the organization and nucleotide sequence of two related genomic sequences. One (CR-1) corresponds to the structural gene encoding the human CRIPTO protein...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Cell Line
- Chromosome Mapping
- Chromosomes, Human, Pair 3
- Epidermal Growth Factor
- GPI-Linked Proteins
- Growth Substances
- Humans
