Article
[The isolation and characteristics of reassortants between the Lassa and Mopeia arenaviruses].
Voprosy virusologii - 1 Jan 2000
Lukashevich I S, Vasiuchkov A D, Stel'makh T A, Scheslenok E P, Shabanov A G
Abstract excerpt
Reassortants with a mixed phenotype were produced by combined inoculation of Vero cells with Lassa and Mopeya viruses. These reassortants produced small plaques (Mopeya virus phenotype) and were not pathogenic for newborn mice (Lassa virus phenotype). The genotype of the reassortants was studied...
Topics
- Animals
- Arenaviridae
- DNA
- DNA Probes
- Genotype
- Lassa virus
- Nucleic Acid Hybridization
- Phenotype
- RNA, Viral
- Recombination, Genetic
- Vero Cells
- Viral Plaque Assay
- Virus Cultivation