Article
Reassortment between two serologically unrelated bluetongue virus strains is flexible and can involve any genome segment.
Journal of virology - 1 Jan 2013
Shaw Andrew E, Ratinier Maxime, Nunes Sandro Filipe, Nomikou Kyriaki, Caporale Marco, Golder Matthew, Allan Kathryn, Hamers Claude, Hudelet Pascal, Zientara Stéphan, Breard Emmanuel, Mertens Peter, Palmarini Massimo
Abstract excerpt
Coinfection of a cell by two different strains of a segmented virus can give rise to a "reassortant" with phenotypic characteristics that might differ from those of the parental strains. Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) segmented virus and the cause of bluetongue, a major infectious disease of livestock. BTV exists as at least 26 different serotypes (BTV-1 to BTV-26). Prompted by the...
Topics
- Animals
- Bluetongue virus
- Genome, Viral
- Genotype
- Mice
- Molecular Sequence Data
- Phenotype
- RNA, Viral
- Reassortant Viruses
- Recombination, Genetic
- Reverse Genetics
- Sequence Analysis, DNA
- Viral Plaque Assay