Article
Generation of reassortants between African arenaviruses.
Virology - 1 Jun 1992
Lukashevich I S
Abstract excerpt
Lassa (LAS) and Mopeia (MOP) viruses are African arenaviruses which are carried by wild rodents and occasionally transferred to humans. In humans and nonhuman primates, Lassa causes mortality in 60% of untreated cases, whereas Mopeia does not cause mortality and has been known to protect monkeys from lethal challenge with Lassa. These two African arenaviruses also differ in their lethality for suckling outbred...
Topics
- Animals
- Antigens, Viral
- Arenaviridae
- Genotype
- Immunization, Passive
- Lassa virus
- Mice
- Nucleic Acid Hybridization
- Phenotype
- RNA, Viral
- Recombination, Genetic