Article
Cut mutant Drosophila auditory organs differentiate abnormally and degenerate.
Fly - 1 Jan 2000
Ebacher Dominic J S, Todi Sokol V, Eberl Daniel F, Boekhoff-Falk Grace E
Abstract excerpt
The Drosophila antenna is a sophisticated structure that functions in both olfaction and audition. Previous studies have identified Homothorax, Extradenticle, and Distal-less, three homeodomain transcription factors, as required for specification of antennal identity. Antennal expression of cut is activated by Homothorax and Extradenticle, and repressed by Distal-less. cut encodes the Drosophila homolog of human...
Topics
- Animals
- Deafness
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- Homeodomain Proteins
- Integumentary System
- Mutation
- Neurons
- Nuclear Proteins
- Sense Organs