Article
[Hereditary thyroid cancer].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen - 1 Nov 2008
Dralle H, Machens A, Lorenz K
Abstract excerpt
Hereditary thyroid carcinomas are present in about 5% of differentiated (DTC) and 25% of medullary thyroid carcinomas (MTC). They are part of a multiorgan tumour syndrome (e. g. FAP Gardner's syndrome with DTC and MEN 2 syndrome with MTC) or confined to the thyroid gland. Hereditary thyroid carcinomas typically show multifocal growth and occur in young patients. Due to germ cell mutations as the underlying cause...
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