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The mammary microenvironment alters the differentiation repertoire of neural stem cells

22 Sept 2008

Abstract excerpt

A fundamental issue in stem cell biology is whether adult somatic stem cells are capable of accessing alternate tissue sites and continue functioning as stem cells in the new microenvironment. To address this issue relative to neurogenic stem cells in the mouse mammary gland microenvironment, we mixed wild-type mammary epithelial cells (MECs) with bona fide neural stem cells (NSCs) isolated from WAP-Cre/Rosa26R...

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PMID: 18809919
DOI: 10.1073/pnas.0803214105

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