EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes.

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Article

EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes.

Molecular vision - 15 Sept 2008

Li Haitao, Louey Janice W C, Choy Kwong Wai, Liu David T L, Chan Wai Man, Chan Yiu Man, Fung Nicholas S K, Fan Bao Jian, Baum Larry, Chan Juliana C N, Lam Dennis S C, Pang Chi Pui

Abstract excerpt

PURPOSE: We tested the hypothesis that genetic variants in vasoactive and angiogenic factors regulating the retina vasculature contribute to the development of diabetic retinopathy (DR). METHODS: A case-control study was performed to study the genetic association between DR and polymorphic variants of EDN1 (Lys198Asn), LTA (IVS1-80C>A, IVS1-206G>C, IVS1-252A>G), eNOS (Glu298Asp), and ITGA2 (BgI II) in a Chinese...

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Identifiers

PMID: 18806884
PMCID: PMC2538496

Genes

EDN1
ITGA2
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.