Article
Smoking and serum CA19-9 levels according to Lewis and secretor genotypes.
International journal of cancer - 15 Dec 2008
Kawai Sayo, Suzuki Koji, Nishio Kazuko, Ishida Yoshiko, Okada Rieko, Goto Yasuyuki, Naito Mariko, Wakai Kenji, Ito Yoshinori, Hamajima Nobuyuki
Abstract excerpt
CA19-9, a marker for cancers of biliary tract, pancreas and colorectum, is not synthesized in those with no enzyme activity genotype (le/le) of Lewis (Le) gene. No enzyme activity genotype (se/se) of secretor (Se) gene is known to have an association with high serum CA19-9 levels. There are also variations in serum CA19-9 levels independent of the genotypes. This study aimed to examine the associations of serum...
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