Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene Expression Profiling to Identify the Histogenetic Origin of Metastatic Adenocarcinomas of Unknown Primary

18 Sept 2008

Abstract excerpt

PURPOSE: Patients with adenocarcinoma of unknown primary origin (ACUP) constitute approximately 4% of all malignancies. For effective treatment of these patients, it is considered optimal to identify the primary tumor origins. Currently, the success rate of the diagnostic work-up is only 20% to 30%. Our goal was to evaluate the contribution of gene expression profiling for routine clinical practice in patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Diagnosis and Treatment
Share to Head and Neck Cancer Studies
Share to Metastasis and carcinoma case studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18802156
DOI: 10.1200/jco.2007.14.6969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene Expression Profiling to Identify the Histogenetic Origin of Metastatic Adenocarcinomas of Unknown PrimaryPMID 18802156Read ↗

An Expression-Based Site of Origin Diagnostic Method Designed for Clinical Application to Cancer of Unknown OriginSemantic proximity Read ↗

Application of Transcriptome–Based Gene Set Featurization for Machine Learning Model to Predict the Origin of Metastatic CancerSemantic proximity Read ↗

Cancer of unknown primary.Semantic proximity Read ↗

Markers of Adenocarcinoma Characteristic of the Site of Origin: Development of a Diagnostic AlgorithmSemantic proximity Read ↗

Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site: New Routes to Targeted Therapies.Semantic proximity Read ↗

Implementation of a novel microarray‐based diagnostic test for cancer of unknown primarySemantic proximity Read ↗

Pan-cancer machine learning predictors of primary site of origin and molecular subtypeSemantic proximity Read ↗

Identification of tissue of origin in carcinoma of unknown primary with a microarray-based gene expression testSemantic proximity Read ↗

Genetic mutations in metastatic adenocarcinoma of unknown primary.Semantic proximity Read ↗

Multicenter Validation of a 1,550-Gene Expression Profile for Identification of Tumor Tissue of OriginSemantic proximity Read ↗

Metastatic Carcinoma of Unknown PrimarySemantic proximity Read ↗

Carcinoma of Unknown Primary Origin: Application of ImmunohistochemistrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.