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Article

Multicenter Validation of a 1,550-Gene Expression Profile for Identification of Tumor Tissue of Origin

31 Mar 2009

Abstract excerpt

PURPOSE: Malignancies found in unexpected locations or with poorly differentiated morphologies can pose a significant challenge for tissue of origin determination. Current histologic and imaging techniques fail to yield definitive identification of the tissue of origin in a significant number of cases. The aim of this study was to validate a predefined 1,550-gene expression profile for this purpose. METHODS: Four...

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PMID: 19332734
DOI: 10.1200/jco.2008.17.9762

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