Article
Rhesus angiotensin converting enzyme 2 supports entry of severe acute respiratory syndrome coronavirus in Chinese macaques.
Virology - 10 Nov 2008
Chen Yunxin, Liu Li, Wei Qiang, Zhu Hua, Jiang Hong, Tu Xinming, Qin Chuan, Chen Zhiwei
Abstract excerpt
Angiotensin converting enzyme 2 (ACE2) is the receptor that severe acute respiratory syndrome coronavirus (SARS-CoV) utilizes for target cell entry and, therefore, plays an important role in SARS pathogenesis. Since Chinese rhesus (rh) macaques do not usually develop SARS after SARS-CoV infection...
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