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Article

Polymorphisms of homocysteine metabolism are associated with intracranial aneurysms.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2008

Semmler Alexander, Linnebank Michael, Krex Dietmar, Götz Anika, Moskau Susanna, Ziegler Andreas, Simon Matthias

Abstract excerpt

BACKGROUND: Impaired homocysteine metabolism is associated with a number of vasculopathies including extracranial aneurysms. We analyzed the possible association of nine genetic variants of homocysteine metabolism with the occurrence of intracranial aneurysms. METHODS: Caucasian patients (n = 255) treated at two German hospitals for intracranial aneurysms and local controls (n = 348) were genotyped for the...

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Source

Identifiers

PMID: 18799873
DOI: 10.1159/000155638

Genes

CBS
DHFR
MTHFR
RFC1
GSTO1
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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