Article
The Cellvibrio japonicus mannanase CjMan26C displays a unique exo-mode of action that is conferred by subtle changes to the distal region of the active site.
The Journal of biological chemistry - 5 Dec 2008
Cartmell Alan, Topakas Evangelos, Ducros Valérie M-A, Suits Michael D L, Davies Gideon J, Gilbert Harry J
Abstract excerpt
The microbial degradation of the plant cell wall is a pivotal biological process that is of increasing industrial significance. One of the major plant structural polysaccharides is mannan, a beta-1,4-linked d-mannose polymer, which is hydrolyzed by endo- and exo-acting mannanases. The mechanisms by which the exo-acting enzymes target the chain ends of mannan and how galactose decorations influence activity are...
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