Lactase persistence-related genetic variant: population substructure and health outcomes.

doi:10.1038/ejhg.2008.156

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Article

Lactase persistence-related genetic variant: population substructure and health outcomes.

European journal of human genetics : EJHG - 1 Mar 2009

Smith George Davey, Lawlor Debbie A, Timpson Nic J, Baban Jamil, Kiessling Matt, Day Ian N M, Ebrahim Shah

Abstract excerpt

Lactase persistence is an autosomal-dominant trait that is common in European-derived populations. A basic tendency for lactase persistence to increase from the southeast to the northwest across European populations has been noted, but such trends within countries have not been extensively studied. We genotyped the C/T(-13910) variant (rs4988235) that constitutes the putatively causal allele for lactase...

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PMID: 18797476
DOI: 10.1038/ejhg.2008.156
PMCID: PMC2986166

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