Article
Pro12Ala polymorphism in PPAR gamma 2 associated with essential hypertension in Chinese nonagenarians/centenarians.
Experimental gerontology - 1 Dec 2008
Lu Zhenchan, Dong Birong, Mo Xianming, Chen Tie, Wu Hongmei, Zhang Yanling, Xiao Hengyi
Abstract excerpt
The Pro12Ala polymorphism of PPAR gamma 2 has been shown to influence hypertension and the benefit of longevity in previous studies. We examined whether the polymorphism was related to essential hypertension among long-lived subjects (is greater than 90 years). The Pro12Ala variant was examined using polymerase chain reaction restriction fragment length polymorphism in a population-based sample of 839 long-lived...
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