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Article

Longitudinal decline in lung volume in a population of children with sickle cell disease.

American journal of respiratory and critical care medicine - 15 Nov 2008

MacLean Joanna E, Atenafu Eshetu, Kirby-Allen Melanie, MacLusky Ian B, Stephens Derek, Grasemann Hartmut, Subbarao Padmaja

Abstract excerpt

RATIONALE: Sickle cell disease (SCD) results in significant morbidity and mortality attributable to pulmonary complications. The pattern of lung function change across childhood in SCD is not well delineated. OBJECTIVES: To determine if the pattern of lung function in SCD differs from race-matched, predicted values across childhood, to describe that pattern of change, and to examine the effect of clinical...

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Topics

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Share to Adolescent
Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forced Expiratory Volume

Share to Genetic Predisposition to Disease

Share to Hemoglobin, Sickle

Share to Longitudinal Studies

Source

Identifiers

PMID: 18776149
DOI: 10.1164/rccm.200708-1219OC

Genes

SCD
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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