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Article

Age is a predictor of a small decrease in lung function in children with sickle cell anemia

11 Dec 2017

Abstract excerpt

Abstract The longitudinal pattern of lung function in children with sickle cell anemia (SCA) has shown a decrease in FEV1% predicted, a risk factor for death in adults with SCA, but predictors for this decline are poorly characterized. In a prospective longitudinal multi‐center cohort of children with SCA, we tested the hypotheses that: (1) FEV1% predicted declines over time; and (2) SCA‐specific characteristics...

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PMID: 29226507
DOI: 10.1002/ajh.25003

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