Article
High prevalence of prolonged norovirus shedding and illness among hospitalized patients: a model for in vivo molecular evolution.
The Journal of infectious diseases - 1 Oct 2008
Siebenga J Joukje, Beersma Mathias F C, Vennema Harry, van Biezen Paula, Hartwig Nico J, Koopmans Marion
Abstract excerpt
During a 2-year survey in an academic hospital, 8 (8.4%) of all norovirus (NoV)-positive patients showed prolonged norovirus illness and shedding (duration, 21-182 days). All patients had underlying illnesses, resulting in some level of immunodeficiency in 5. Four patients were admitted to the hospital with gastroenteritis, 2 acquired norovirus while hospitalized, and 2 were outpatients. Genotypes GII.4 and...
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