Article
Expectations and challenges stemming from genome-wide association studies.
Mutagenesis - 1 Nov 2008
Vineis Paolo, Brennan Paul, Canzian Federico, Ioannidis John P A, Matullo Giuseppe, Ritchie Marylyn, Stromberg Ulf, Taioli Emanuela, Thompson John
Abstract excerpt
There are considerable expectations about the ability of genome-wide association (GWA) studies to make exciting discoveries about the role of genes in common diseases. GWA studies may allow researchers to identify causal pathways that have not been unveiled before, thus opening new avenues to disease understanding, prevention and therapy. However, there are still many open challenges. One is how to analyse these...
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