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Article

Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms.

Arthritis and rheumatism - 1 Sept 2008

Zhang Kejian, Biroschak Jennifer, Glass David N, Thompson Susan D, Finkel Terri, Passo Murray H, Binstadt Bryce A, Filipovich Alexandra, Grom Alexei A

Abstract excerpt

OBJECTIVE: Systemic juvenile idiopathic arthritis (JIA) is associated with macrophage activation syndrome. Macrophage activation syndrome bears a close resemblance to familial hemophagocytic lymphohistiocytosis (HLH). The development of familial HLH has been recently associated with mutations in...

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Identifiers

PMID: 18759271
DOI: 10.1002/art.23734
PMCID: PMC2779064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18759271-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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